GSTA3 anticorps (Middle Region)

N° du produit ABIN2783389

Cet anticorps Lapin Polyclonal détecte spécifiquement GSTA3 dans WB. Il présente une réactivité envers Humain, Souris et Mouton.

Aperçu rapide pour GSTA3 anticorps (Middle Region) (ABIN2783389)

Antigène: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Reactivité: Humain, Souris, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTA3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GSTA3 anticorps

Épitope: Middle Region

Séquence: SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR

Homologie: Human: 100%, Mouse: 79%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against GSTA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GSTA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 222 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GSTA3

Antigène: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Autre désignation: GSTA3

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3-3, GTA3, MGC22232
Protein Interaction Partner: BAG3, APP,
Protein Size: 222

Poids moléculaire: 25 kDa

ID gène: 2940

NCBI Accession: NM_000847, NP_000838

UniProt: Q16772